Contents

What Is Cold Plasma? How Does It Affect Hair?

Introduction: A New Technology in Hair Health

In recent years, cold plasma technology has become one of the most remarkable innovations in hair health and post–hair transplant care. Cold plasma provides strong biological stimulation at the cellular level, supporting the regeneration of hair follicles and restoring a healthy microenvironment in the scalp. Its greatest advantage is that it works without generating heat, without damaging the skin, and in a completely non-invasive way.

Scientific Basis of Cold Plasma

Plasma is defined as the fourth state of matter after solid, liquid, and gas. Cold plasma is a special form produced at low temperature and contains the following active components:

– Reactive oxygen species (O, O3, OH•, H2O2, etc.)

– Reactive nitrogen species (NO, NO2, N2O, etc.)

– Free radicals

– Ions, electrons

– UV photons

When applied to the scalp, these components create controlled biostimulation, increasing cellular activity. Because it does not generate harmful heat levels, the process is known as “cold plasma.”

Effects of Cold Plasma on Hair and Scalp

1-Enhances Microcirculation

One of the main causes of hair loss is insufficient oxygen and nutrient delivery to the follicles. Cold plasma:

– Increases blood flow in the scalp

– Enhances local oxygenation

– Improves follicle nutrition

– Revitalizes weakened hair

This effect helps slow down follicle miniaturization in androgenetic alopecia and improves hair quality.

2-Stimulates Dermal Papilla Cells

The dermal papilla is the main cellular command center controlling hair growth. Cold plasma:

– Increases cell proliferation

– Speeds up follicular metabolism

– Supports the anagen (growth) phase

– Activates signals responsible for new hair formation

Regular sessions shorten the telogen resting phase and accelerate visible hair growth.

3-RONS Effect: Controlled Biostimulation

The most important component of cold plasma is RONS — Reactive Oxygen and Nitrogen Species.

At low doses, RONS:

– Provide anti-inflammatory effects

– Accelerate tissue repair

– Activate intracellular signaling pathways

– Trigger regeneration within the hair follicle

Controlled RONS exposure shifts follicles into a repair and renewal mode.

4-Antibacterial and Antifungal Cleansing

Cold plasma has a natural sterilizing effect. Therefore, it:

– Reduces dandruff

– Improves scalp fungal infections and folliculitis

– Balances excessive oil production

– Helps normalize the scalp microbiome

This antibacterial effect also reduces infection risk after hair transplantation.

5-Accelerates Post–Hair Transplant Healing

Cold plasma is one of the fastest-growing postoperative care methods in hair transplant centers. When applied immediately after transplantation or on Day 1:

– Increases tissue oxygenation

– Helps reduce necrosis risk

– Minimizes swelling and redness

– Improves graft survival and attachment

– Speeds up crust formation and healing

– Reduces inflammation-related complications

RONS contributes significantly to rapid, controlled tissue recovery.

6-Strengthens Hair Structure

Cold plasma also affects newly growing hair:

– Thickens hair strands

– Increases resistance to breakage

– Enhances elasticity

– Improves shine and overall hair health

This makes it beneficial even for individuals who have not undergone a transplant.

Indications for Cold Plasma Use

Cold plasma is effective in:

– Male pattern hair loss (AGA)

– Female pattern hair loss (FAGA)

– Pre–hair transplant preparation

– Post–hair transplant healing

– Dandruff, dermatitis, folliculitis, fungal issues

– Thin, weak, and fragile hair

How Is the Procedure Performed?

– The application is non-invasive—no needles or injections.

– Plasma energy is applied to the scalp surface in a controlled manner.

– The session takes approximately 8–12 minutes.

– No pain, heat, or discomfort is felt.

– The patient may immediately return to daily activities.

Conclusion

Cold plasma is a modern technology that restores the biological balance of the scalp, stimulates hair follicles, and accelerates healing. It stands out with high success rates, safe application, and rapid recovery in both hair loss patients and individuals who have undergone a hair transplant.